Recombinant antibodies for therapy

Antibodies, also known as immunoglobulins (Ig), are supramolecular protein complexes that belong to the immune system. Antibodies are designed and produce by leucocytes (precisely, B cells) when foreign agents, such as bacteria, parasytes or viruses, invade our organism. Antibodies have the particular ability for recognizing and binding with great affinity these exogenous agents, so that

Neurodegeneration and memory impairment

Memory and learning impairment is a hallmark in many neurodegenerative diseases, such as Alzheimer’s disease and Parkinson’s disease. However, even these diseases share some features, the time of manifestation and symptons are subtly different. In fact, different brain regions and neuron types might be involved in the pathophysiology of each neurodegenerative disease. Nevertheless, one of

DNA ez da dena: epigenetikaren garrantzia

DNA-k (ingelesetik, deoxyribonucleic acid) geneak ditu kodeturik bere sekuentziaren baitan, azido nukleikoen segida moduan; hori horela izanik, izaki bakoitzaren genoman kodeturiko geneen multzoak fenotipo desberdinak determinatuko ditu. Bestalde, fenotipoa ez dago guztiz determinaturik kodeturiko geneengatik; izan ere, geneak nola adierazten diren, fenotipoa desberdina izango da. Fenomeno hau agerikoa da izaki zelulanitzen garapenean: zelula guztiek genoma

Ezagutu zure burmuina: zenbat neurona mota ditugu?

Giza burbuina konplexutasun handieneko ehuna dugu, 100 bilioi neurona zelula dituelarik. Neuronak talde eta azpitalde ugaritan banatu daitezke, ezaugarri eta propitate morfologiko eta fisiologiko espezifiko eta bakarrek determinaturik. Szentágothai-ren lanean 50 neurona mota baino gehiago deskribatzen dira, besteak beste zelula piramidal, zelula izartu, Purkinje zelulak, Martinotti zelulak eta zelula mitralak. Bestalde, neurona guztiek oinarrizko diseinua